Ekaterinburg, Ekaterinburg, Russian Federation
Ekaterinburg, Ekaterinburg, Russian Federation
Clinical studies indicate that products from cow colostrum are well tolerated by the human body, non-toxic and safe for consumption. The aim of this study is to study the antitumor properties of isolated individual peptides from corvine colostrum on the cell line of rat glioblastoma C6. The study revealed that peptide R1 has antitumor activity, therefore it can be used as a functional ingredient in food products.
peptides, bovine colostrum, enzymatic hydrolyzate, prophylactic products
1. Barati, M., Javanmardi, F., Mousavi Jazayeri, S. M. H., Jabbari, M., Rahmani, J., Barati, F., Nickho, H., Davoodi, S. H., Roshanravan, N., & Mousavi Khanegah, A. Techniques, perspectives, and challenges of bioactive peptide generation: A comprehensive systematic review. 2020. 19 (4), S. 1488-1520. http://dx.doi.org/10.1111/1541-4337.12578;
2. Mehra R, Garhwal R, Sangwan K, et al. Insights into the Research Trends on Bovine Colostrum: Beneficial Health Perspectives with Special Reference to Manufacturing of Functional Foods and Feed Supplements. Nutrients. 2022. 14 (3). S. 659;
3. Navarro-Peraza, R. S., Osuna-Ruiz, I., Lugo-Sánchez, M. E., Pacheco-Aguilar, R., Ramírez-Suárez, J. C., Burgos-Hernández, A., Martínez-Montaño, E., & Salazar-Leyva, J. A.. Structural and biological properties of protein hydrolysates from seafood by-products: a review focused on fishery effluents. Food Science and Technology, 2020. 40 (1), S. 1-5;
4. Rafiq, S., Gulzar, N., Sameen, A., Huma, N., Hayat, I., & Ijaz, R. Functional role of bioactive peptides with special reference to cheeses. International Journal of Dairy Technology. 2021. 74 (1), S. 1-16;
5. Shi, T., & Li, Y. Producing high Fischer ratio peptides from milk protein and its application in infant formula milk powder. 2021. 13 (1), S. 49-58. https://doi.org/10.15586/qas.v13i1.808.
