Abstract and keywords
Abstract (English):
Purpose: to study the relationship between the dose of active ribosomal genes and the level of chromosomal aberrations in coal mine workers. Chromosomal aberrations were studied in 357 miners and 736 men who do not work at industry. The dose of active ribosomal assessed in 154 miners and 91 people from the comparison group. Identified increase in the frequency of occurrence of single fragments in workers with an average dose of active ribosomal genes.

Keywords:
chromosomal aberrations, miners, dose of active ribosomal genes
Text
Text (PDF): Read Download
References

1. Ulker, O.C. Cytogenetic monitoring of coal workers and patients with coal workers' pneumoconiosis in Turkey / Ulker, O.C., Ustundag, A., Duydu Y., et al. // Environ Mol. Mutagen. - 2008. - V. - № 3. - P. 232-237.

2. León-Mejía, G. Genetic damage in coal miners evaluated by buccal micronucleus cytome assay / León-Mejía, G., Quintana, M., Debastiani, R., et al. // Ecotoxicol Environ Saf. - 2014. - № 107. - P. 133-139.

3. Minina, V.I. Genomic dosages of active rRNA genes in coke-oven workers / Minina, V.I., Druzhinin, V.G. // Russian Journal of Genetics. - 2004. - V. 40. - № 12. - P. 1702-1708.

4. Hungerford, P.A. Leukocytes cultured from small inocula of whole blood and the preparation of metaphase chromosomes by treatment with hypotonic KCl / Hungerford, P.A. // Stain Techn. - 1965.- № 40. - P. 333-338.

5. Howell, W.M. Controlled silver-staining of nucleolus organizer regions with a protective colloidal developer: a1-step method / Howell, W.M., Black, DA. // Experientia. 1980. - № 36. - P. 1014-1015.

6. Lyapunova, N.A. Ribosomnye geny v genome cheloveka: vklad v geneticheskuyu individual'nost' i fenotipicheskoj proyavlenie dozy gena / Lyapunova, N.A. // Vestn. Ros. AMN. - 2000. - №5. - P. 19-23.

7. Medvedev, I. N. Vyrazhennost' khromosomnykh aberratsii i aktivnost' yadryshkoobrazuyushchikh raionov khromosom sredi korennykh zhitelei Kurskogo regiona / Medvedev, I. N., Amelina, I. V. // Vestnik Moskovskogo universiteta. - 2014. - Seriya 23, Antropologiya. - №2. - P. 109-113.

Login or Create
* Forgot password?