Development of technological entrepreneurship is one of the strategic priorities of Russia's core universities. A number of universities in the country have already accumulated a certain experience in teaching technology entrepreneurship. Formation of basic universities as centers of strategic development of the region and its single-industry towns requires the development of new approaches to training in technological entrepreneurship. The article deals with the mechanism of constructing an innovative ecosystem that promotes the formation of entrepreneurial competencies in the students of the supporting university. The research is based on the case of the Kemerovo region and features the main characteristics and tasks of the system of teaching technological entrepreneurship in its flagship university, taking into account
the strategy and key problems of the region. The paper reveals the key features of teaching technological entrepreneurship in regions with a predominance of mono-profile municipal entities. It introduces potential directions of development of technological entrepreneurial initiatives related to overcoming the mono-dependence of the cities of the Kemerovo region. The results can be used in teaching technological entrepreneurship for the benefit of single-industry towns, as well as in compiling municipal order for educational services.
oneindustry town, traditional industrial region, technological entrepreneurship, innovation ecosystem, supporting university